Lancet Commission: AI misuse and nuclear war could cause human extinction by 2100

A newly established Lancet commission on global health threats in the 21st century has published a global risk assessment, according to a report by The Guardian. The commission lists 17 major threats to human health over the next 75 years. At the top of the list are malicious use of AI and nuclear conflict, which the commission says could lead to human extinction by the year 2100. Other threats named in the list include cuts to aid spending by wealthy countries, the climate crisis and childhood malnutrition. The commission stresses that these threats are interconnected and must be addressed together, while stating that a "realistic route to act" exists for each of them. The assessment was reported on October 11, 2026, and no further details on specific action plans from the commission have been reported so far.