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Claude Sonnet 5 autonomously selects a gene therapy and injects it into mouse brains

10/31/2026 — 10/31, 04:17·1 sources (all)·1 reports (all)

Key takeaways

  • Gabriel Ocana-Santero, co-founder of Exin Therapeutics and a Oxford PhD student, said on X that his team gave Claude Sonnet 5 a list of 19 c…

Background & analysis

According to a report by The Decoder on October 31, 2026, Gabriel Ocana-Santero, co-founder of Exin Therapeutics and an Oxford University PhD student, said on X that his team handed Claude Sonnet 5 a list of 19 candidate gene therapies, an epilepsy mouse model and a camera-equipped surgical setup, and that the model then chose the drug, the target brain region and the stereotactic coordinates on its own before performing the injection. Ocana-Santero described this as the first time an AI agent has autonomously selected a treatment and delivered it to a living mammal. The report adds that when a calibration error occurred midway through the procedure, the agent refused to bypass the safety restriction and could not be persuaded to proceed. As of now the claim rests solely on the researcher's own account on X and The Decoder's coverage, with no independent verification.

AI-generated from 1 reports · updated 6 days ago

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Reports on this story headlines open the original

Oct 31
  1. Writing on X, Exin Therapeutics cofounder and Oxford PhD student Gabriel Ocana-Santero said his team gave Claude Sonnet 5 a list of 19 candidate gene therapies, an epilepsy mouse model and a camera-equipped surgical rig; the model chose the drug, brain region and stereotactic coordinates and performed the injection itself. When a calibration error struck mid-procedure, it refused to bypass a safety restriction, and he describes it as the first time an AI agent has chosen and delivered a treatment to a living mammal.

    The DecoderAI score 70

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